CD14 anticorps (FITC)

N° du produit ABIN120557

L’anticorps Souris Monoclonal anti-CD14 a été validé pour FACS. Il convient pour détecter CD14 dans des échantillons de Humain et Primate.

Aperçu rapide pour CD14 anticorps (FITC) (ABIN120557)

Antigène: CD14

Reactivité: Humain, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD14 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: MEM-18

Détail du produit anti-CD14 anticorps (FITC)

Immunogène: A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: Analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS pH 7.4 containing 15 mM Sodium Azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody in the dark at 2-8 °C. Do Not Freeze. Avoid prolonged exposure to light.
Shelf Life: One year from despatch.

Date de péremption: 12 months

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor, it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

UniProt: P08571

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades